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Thursday, November 14, 2002
Keynote Speaker
• Donald B. Kohn, M.D. (Childrens Hospital Los Angeles)
"Gene Therapy Using Hematopoietic Stem Cells"
Presentation Topic: Vectors
• John J. Rossi, Ph.D. (City of Hope National Medical Center)
“Combinatorial Ribozyme, Decoy and Sirna Therapies for HIV-1”
• Bruce A. Bunnell, Ph.D. (Tulane University Health Sciences Center)
"Analysis of Gene Transfer Efficiency and Gene Expression with Equine Infectious Anemia Virus (EIAV) Derived Lentivirus Vectors"
• James G. Hecker, M.D., Ph.D. (University of Pennsylvania)
"Non-Viral Gene Delivery for Selected Clinical Applications"
Student/Fellow Presentations
• Kolbot By, B.S. (UC Davis)
"Synthesis of PH-Vulnerable Amphiphiles for Gene Therapy"
• Chang I. Lee, B.S. (UC Davis)
"Transduction of Fetal Monkey Mesenchymal Stem Cells with Lentiviral Vectors"
• Mingjie Li, Ph.D. (City of Hope National Medical Center)
"Inhibition of HIV-1 Infection by Lentiviral Vector Carrying ANTI-CCR-5 Ribozyme and Tar Decoy"
• Carolyn Lutzko, Ph.D. (Childrens Hospital Los Angeles)
"Development of Lentiviral Vectors with Position Independent Transgene Expression in Human and Murine B-Lymphoid Cells"
• Natalya Perelman, M.S. (Childrens Hospital Los Angeles)
"Enthyroid-Specific Self-Inactivating Lentiviral Vectors Suffer from Position Effects"
• Patrick L. Sinn, Ph.D. (University of Iowa)
"Pseudotyping Feline Immunodeficiency Virus (FIV)-Based Vectors to Target the Apical Surface of Differentiated Human Airway Epithelia"
Presentation Topic: Heart, Lung, and Blood
• Judith A. St. George, Ph.D. (Genzyme Corporation)
"Results of Phase I Gene Therapy Clinical Trials for Cystic Fibrosis: Answers but More Questions"
• Paul B. McCray, M.D. (University of Iowa)
"Pseudotyping Lentiviral Vectors for Therapeutic Targets"
• Karin M. Gaensler, M.D. (UC San Francisco)
"Viral-Mediated In Utero Gene Transfer to the Developing Mouse Fetus"
• Alice F. Tarantal, Ph.D. (UC Davis)
"Fetal Gene Therapy for Congenital Heart, Lung, and Blood Diseases - A Future Reality?"
Practical Strategies: Stem Cells
• Gay M. Crooks, M.D. (Childrens Hospital Los Angeles)
"Isolation and Assay of Hematopoietic Stem Cells"
Dinner Speaker
• Inder M. Verma, Ph.D. (The Salk Institute)
"Gene Therapy: Medicine of the 21st Century"
Friday, November 15, 2002
Workshop: Human Embryonic Stem Cells
• Meri T. Firpo, Ph.D. (UC San Francisco)
"Derivation and Differentiation of Human Embryonic Stem Cells"
Session I
• Connie J. Eaves, Ph.D. (The Terry Fox Laboratory)
"Hematopoietic Stem Cells – Lessons for Gene Therapy"
• Robert G. Andrews, M.D. (Fred Hutchinson Cancer Research Center)
"Gene Transfer into Hematopoietic Stem Cells of Non-Human Primates"
• Morton J. Cowan, M.D. (UC San Francisco)
"In Utero Hematopoietic Stem Cell Transplantation: The Issue of 'Space' "
• Stanton L. Gerson, M.D. (Case Western Reserve University)
"Stem Cell Selection In Vivo Using the MGMT Drug Resistance Gene "
Student/Fellow Presentations
• Sawati Bhattacharyya, Ph.D. (UC San Francisco)
"Role of Co-Stimulatory Molecules in Alloengraftment Post In Utero Transplantation"
• Michael E. Bowdish, M.D. (University of Southern California)
"Use of an Aortic Pouch Model to Capture Blood-Circulating Mesenchymal Stem Cells"
• Jason E. Ekert, Ph.D. (UC Davis)
"In Vitro Characterization of Rhesus Monkey Bone Marrow-Derived Mesenchymal Stem Cells from Fetal and Juvenile Donors"
• Li Liu, Ph.D. (UC Davis)
"Liposome-Mediated Extracellular Superoxide Dismutase Gene Delivery Protects Against Reactive Oxygen Species-Associated Hepatocellular Injury In Vitro and In Vivo"
• Ryan Rodriguez, B.S. (UC San Francisco)
"Genetic Modification of Embryonic Stem Cells"
• Steven Zielske, M.A. (Case Western Reserve University)
"Human NOD/SCID Repopulating Cells Lentivirus-Transduced with P140K MGMT have a Selective Advantage and are Enriched In Vivo after BG/BCNU Treatment without Pre-Transplant Irradiation Conditioning"
Session II
• Jan A. Nolta, Ph.D. (Washington University)
"Human Mesenchymal Stem Cell Trafficking Studies are Facilitated by Novel Murine Xenotransplantation Models"
• Victor K. Han, M.D., F.R.C.P. (Child Health Research Center)
"Human Stem Cells from Cord Blood and Placenta: Potential Sources of Regenerative and Transplant Therapy for Newborns and Children"
• David R. Warburton, D.S.C., M.D., F.R.C.P. (Childrens Hospital Los Angeles)
"Stem Cells in Lung Morphogenesis, Repair, and Regeneration"
Concluding Comments
• Alice F. Tarantal, Ph.D. (UC Davis)
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